Difference between progynova and other brands?

Shazi · 2023-06-07T11:24:43+00:00

I saw progynova 2mg costs 540 something and many other brands of 2mg estradiol like estova by cipla or endonorm ev2 cost around 288-315 something like this,...

Sutirtha

divya_06235 Btw why do you say that its useless? My doc has prescribed Progynova 2mg

Ruhanika

I am also prescribed 1mg progynova along with diane 35 as anti-androgen.
It's the initial phase... Just 6 days into HRT.
May I know, does this drug cause harm in long term?
Also, are there better options available?

nobleweather

Ruhanika Progynova doesn't cause any harm in the long term unless and until you have any liver issues. The only issue it might cause is low estrogen levels as Progynova is taken orally and it converts to estrone (a weaker form of estrogen) not estradiol. So check your hormone levels after a month or something to make sure you don't have low estrogen. Diane 35 on the other hand is very risky and has been banned in multiple countries. Diane is a birth control pill which uses ethinyl estradiol, a conjugated estradiol, instead of our bioidentical estradiol so it carries a high risk of life threatening blood clots and heart attacks especially people who have higher body weight or people wgo are exposed to nicotine. Also it's not advisable to stay on Diane for long term. So I would suggest speak with your endo if he can prescribe any other alternative for Diane.

Ruhanika

nobleweather may I know, is aldectone/spironolactone a better option than diane35?
My endo said injections are a better option always... Lupride depot. But since I am too afraid of syringes, I insisted him to prescribe me pills... And hence he prescribed diane35. Otherwise he was giving lupride depot 11.25 mg injection.

Sushmi

Ruhanika Spiro is always a better option and I'm taking that only

Ruhanika

Sushmi ah okay

SophiaUnderShell

Ruhanika lupride depot is the best AA out there with minimal side effects if their marketing is to be believed. I checked the graphs and it is basically nuking testosterone production in 3 weeks time.

Maaya

SophiaUnderShell I agree! LD got amazing results in the beginning of my transition. Only wish I had it from the beginning.

My endo put me on Progynova + AA tablets for the first year. Feminisation effects were minimal - it all went to the chest! But after 12 months, the AA tablets were replaced with LD 11.25mg once in 3 months. Drastic increase in overall effects.

When I was recovering from surgery, I met some girls who had amazing overall feminisation effects and they had always been on a Estradiol injection + Tablet regimen from the beginning. PG is excellent for breast development, but Estradiol injections give the best results. Unfortunately, Estradiol injections are not always available. PG is available everywhere!

mizu

Cyproterone acetate is outdated and no longer used.
Spiro is the standard AA in most western countries due to Lupron being unaffordable. Usage of Lupron seems to be high in India, and it's worked absolutely phenomenally for me so far (3 shots in).

SophiaUnderShell

mizu

mizu Do you take it monthly or is it once in three months?

mizu

SophiaUnderShell Lupron? I'm on the monthly dose right now, just took my third shot.
I presume I will be moved to the 3-monthly dose soon.

Ruhanika

mizu i have heard that taking injection monthly with hike ur hormone level immediately and it can cause damage to some of the organs.

mizu

Ruhanika I think that only happens with the initial shot.
I did not experience any T spike after my second or third shot.
Both 1 and 3-month doses are acceptable doses for cis men and women, from what I have seen.

SophiaUnderShell

mizu But expensive

Pallavi_Verma

I take 3 months one.. from past 7 months never had T go above 10. Quite happy with lupride depot.

mizu

Pallavi_Verma My last reading was below the level of minimum measurement (< 2.5) 😂

SophiaUnderShell

I'm thinking of swapping lupride depot with luprodex depot. Practo has doctors saying it's the same thing. But luprodex is a product of Bharat serums and is almost 500 bucks cheaper. Any takers of luprodex here?

Hasini

SophiaUnderShell I was taking luprodex for more than a year. Yes it's somewhat cheaper then other brands. And they all the same.

mizu

SophiaUnderShell my second shot was Luprodex because I was unable to find Lupron online. It was fine, not only is the composition the same, but my trough value of T as measured before my third shot was also below measurable range. 🙂

SophiaUnderShell

mizu did you ask your endo to change your prescription for that? Where did you order through?

mizu

SophiaUnderShell Huh? Both are Leuprolide Acetate, you don't need to change prescription over a brand name difference... I got both from Pharmeasy.

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